Chronic hepatitis C Infections and Infestations Hepatitis C virus
Conditions
Interventions
All patients who met these criteria randomly chose to be serviced in either of the following two groups:
Group 1 with public health nurse consultation in the outpatient clinic.
Group 2 was offered pho
Sponsors
Department of Health (Taiwan)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Adult patients who have never received interferon and who had at least 2000 copies of HCV ribonucleic acid per ml (RNA/ml) of serum with polymerase chain reaction (PCR) assay, serum aspartate aminotransferase (AST) above the upper limit of normal within six months before entry into study and a liver biopsy result consistent with the diagnosis of chronic hepatitis C.
Exclusion criteria
Exclusion criteria: Patients with: 1. Neutropenia (1.5 times the upper limit of normal 7. Poorly-controlled psychiatric disease 8. Unwilling to receive contraception
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| 1. Serum alanine aminotransferase 2. Aspartate aminotransferase 3. Dropout rate (the number of patients who discontinued treatment prematurely or were lost to follow-up) | — |
Primary
| Measure | Time frame |
|---|---|
| Sustained virologic response (absence of detectable HCV RNA at the end of follow-up with PCR assay) | — |
Countries
Taiwan
Outcome results
None listed