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Antibiotic prophylaxis in varicose vein surgery

A double blinded randomised controlled trial of antibiotic prophylaxis in varicose vein surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN12467340
Enrollment
572
Registered
2004-09-30
Start date
2003-04-09
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery: Varicose vein Surgery Varicose vein

Interventions

1. Antibiotics (Augmentin 1.2 g) 2. No antibiotics The treatment was a one-off treatment (varicose vein surgery), which lasted a range of 44 - 65 minutes. Patients were seen once at 14 days post-ope

Sponsors

Record Provided by the NHSTCT Register - 2004 Update - Department of Health (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Added 13/02/2009: 1. Aged 18 years or older, either sex 2. Undergoing groin surgery for varicose veins. All patients with varicosities of the greater saphenous vein (GSV) listed for saphenofemoral ligation, stripping of the GSV and phlebectomies were eligible to enter the trial.

Exclusion criteria

Exclusion criteria: Added 13/02/2009: 1. Patients whose surgery did not include a groin incision 2. Patients below the age of 18 years 3. Pregnancy or lactation 4. Penicillin allergy 5. Receiving antibiotics for other indications

Design outcomes

Primary

MeasureTime frame
Added 13/02/2009: The degree of wound complications, determined by an adapted version of the ASEPSIS wound scoring system.

Secondary

MeasureTime frame
Added 13/02/2009: 1. Visit to the General Practitioner for a wound-related problem 2. The requirement of antibiotics in the post-operative period for a perceived wound infection

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 1, 2026