Panic disorder, Agoraphobia, Personality disorder Mental and Behavioural Disorders
Conditions
Interventions
Participants will be randomised into one of the two arms:
1. Psychoanalytic therapy (PT)
2. Cognitive-behavior therapy (CBT)
They will be assessed at the study centrebefore treatment, after terminati
Sponsors
German Society for Psychoanalysis, Psychotherapy, Psychosomatics and Depth Psychology (DGPT) (Germany)
Eligibility
Sex/Gender
All
Age
21 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Panic disorder (including partial remission, i.e., maximally 2 months without significant symptoms) and/or agoraphobia plus: 2. At least one of the following PDs: avoidant PD, dependent PD, obsessive-compulsive PD, depressive PD, negativistic PD, histrionic PD, borderline PD without acute suicidality, narcissistic PD, PD not otherwise specified (i.e., in at least two of the PD categories listed above only 1 criterion is missing to fulfill the diagnosis) 3. Age: at least 21 years
Exclusion criteria
Exclusion criteria: 1. Bipolar affective disorder, psychotic disorder, acute eating disorder, substance-related disorder (except caffeine and nicotine), Cluster-A PDs, antisocial PD, borderline PD with acute suicidality 2. Neurological diseases (with psychologically significant consequences, e.g., epilepsy) 3. Insufficient knowledge of the German language 4. Strong preference for one of the two treatment conditions 5. Current medication with benzodiazepine
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome measure as of 23/05/2016: 1. Overall symptomatic burden according to LIFE-interview over the 6 year follow-up-period 2. Individual change in patients self-reports (combination symptomatic burden, SCL-90-GSI, interpersonal problems, IIP, and life satisfaction, FLZ) between beginning of treatment and 6-year-follow-up Original primary outcome measures: 1. Individual change in mental disorders (according to SCID-Interviews, Axis I and Axis II) between beginning of treatment and 6-year-follow-up 2. Individual change in patients self-reports (combination symptomatic burden, SCL-90-GSI, interpersonal problems, IIP, and life satisfaction, FLZ) between beginning of treatment and 6-year-follow-up | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome measure as of 23/05/2016: 1. Individual change in criteria for personality disorders (according to SCID-interview, axis II) 2. Patients Health Questionnaire (PHQ) 3. Assessment of DSM-IV Personality Disorders (ADP-IV) 4. Panik- und Agoraphobieskala (PAS) 5. Experiences in Close Relationships - Revised? (ECR) 6. ?Structural Impairment?, assessed with: Inventory of Personality Organization ? short form (IPO-16), Operationalized Psychodynamic Diagnostics (OPD), and Scales of Psychological Capacities (SPC) 7. Short Form Health Survey (SF-12) 8. Willingness-to-pay (WTP) Original secondary outcome measures: 1. Overall symptomatic burden according to LIFE over the 6 year follow-up-period 2. Patients Health Questionnaire (PHQ) 3. Assessment of DSM-IV Personality Disorders (ADP-IV) 4. Panik- und Agoraphobieskala (PAS) 5. Experiences in Close Relationships - Revised? (ECR) 6. ?Structural Impairment?, assessed with: Inventory of Personality Organization ? short form (IPO-16), Operationalized Psychodynamic Diagnostics (OPD), and Scales of Psychological Capacities (SPC) 7. Short Form Health Survey (SF-12) 8. Willingness-to-pay (WTP) | — |
Countries
Germany
Outcome results
None listed