Healthy individuals Not Applicable
Conditions
Interventions
This study examines the benefits and risks of residing in an environment with blue depleted lighting compared to residing in an environment with normal lighting. The trialists will recruit adult volun
Sponsors
Norwegian University of Science and Technology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age 20-30 years 2. No evidence of circadian dysrhythmia (defined as a self-reported bed-time of about 2300h/2400h and rise-time of about 0700h/0800h and <2 hours variation in bed-time and rise-time between weekdays and weekends 3. Normal color vision 4. No known physical or mental disorder 5. No known family history of severe mental disorder (e.g. unipolar, bipolar, psychotic disorders, etc) 6. Not currently being prescribed any medication
Exclusion criteria
Exclusion criteria: 1. Score on the Morningness-Eveningness Questionnaire (MEQ) that indicates that the individual has an extreme morning or evening chronotype 2. Not fluent in Norwegian
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Melatonin levels assessed using saliva samples: Timing of Dim Light Melatonin Onset (DLMO) after 5 days residency in each ward as compared to baseline; melatonin levels on the 5th evening in each condition compared to melatonin levels in dim light on the 6th evening (melatonin suppression) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Sleep, assessed using: polysomnography on the 4th and 5th evening in each condition; actigraphic recording of sleep-activity cycles and self-rated sleep diaries for 1 week prior to residing at the unit and throughout the study period; Xethru radar assessment of movement when participants are in their rooms, including sleep-activity cycle during residency in each ward 2. Sleepiness, assessed using: Karolinska Sleepiness Scale scored every second hour from 1800h to bedtime and again at 0700h; EEG drowsiness test at 2100h and 2200h the final two evenings in each condition along with Karolinska Sleepiness Scale at 2100h and 2300h 3. Neurocognitive function, assessed using Connors Continuous Performance Test 3 on the third evening in each condition 4. Color discrimination, assessed using the Farnsworth-Munsell 100 hue test on the first evening in each condition 5. Acceptability of lighting, assessed using self-report questionnaires on the first evening in each condition and the final evening in each condition 6. Perceived side-effects of residing in each ward assessed using the UKU questionnaire the day after each condition (6th day) | — |
Countries
Norway
Outcome results
None listed