Universal warming protocol

Testing the efficacy and efficiency of a single “universal warming protocol” for vitrified human embryos: a randomized controlled study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN12342851

Enrollment

Registered

2017-03-24

Start date

2017-03-01

Completion date

Unknown

Last updated

2020-12-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Warming cryopreserved human oocytes Pregnancy and Childbirth

Interventions

All participants undergo controlled ovarian stimulation between day 12 and 20 of their menstrual cycle using gonadotropin-releasing hormone analogs in combination with a graded gonadotropin administra

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Infertile patients 2. Undergoing to fertility treatments via Intracytoplasmic Sperm injection (ICSI) 3. Aged 18 years and over 4. Female

Exclusion criteria

Exclusion criteria: Patients undergoing to preimplanatation genetic screening (PGS)

Design outcomes

Primary

Measure	Time frame
Survival rate (number of embryos surviving per number of embryo warmed) is measured using observation a optical microscope one hour after thawing.	—

Secondary

Measure	Time frame
Implantation rate (number of embryos implanted per number of embryos transferred in utero) is measured using ultrasound observation of gestational sacs at 30 days after the in-utero embryo transfer.	—

Countries

Italy

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 5, 2026