Topic: Eye, Generic Health Relevance and Cross Cutting Themes
Conditions
Interventions
Once participants enter the occlusion phases they are randomised to receive a Personalised Dosing Strategy (PDS) or a Standardised Dosing Strategy (SDS) of occlusion by patching. Those assigned PDS wi
Sponsors
City University London (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The trial will recruit subjects with amblyopia associated with: 1.1. Strabismus 1.2. Anisometropia 1.3. A combination of anisometropia and strabismus 2. Children aged between 3 and 8 years with visual acuity of 0.2 logMAR or lower in the worst eye and an inter-ocular difference of at least 0.2 log units with the presence of anisometropia and/or strabismus and no other ocular pathology including amblyopia associated with form deprivation or previous occlusion treatment history will be eligible for recruitment. 3. Target Gender: Male & Female
Exclusion criteria
Exclusion criteria: 1. Those with other ocular pathology 2. Those with form deprivation amblyopia as this is a minority group and often is linked with other ocular pathology 3. Previous history of treatment for amblyopia 4. Those with learning difficulties and therefore cannot perform an accurate visual acuity test on every occasion tested
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual acuity change; Timepoint(s): Change in visual acuity of the amblyopic eye during treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcome measure will be stereoacuity measured using the Frisby test and the Randot pre-schooler test | — |
Countries
United Kingdom
Outcome results
None listed