The Middlesbrough study: a randomised, controlled trial of dietary supplements with omega-3/omega-6 fatty acids in mainstream school children

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN12286781

Enrollment

250

Registered

2007-09-28

Start date

2005-04-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Poor concentration, hyperactivity, learning abilities and working memory Mental and Behavioural Disorders Mild child/adolescent cognitive disorder

Interventions

Active treatment: dietary supplement (Eye q): Omega-3/omega-6 dietary supplement in capsule form, six times/day providing 558 mg Eicosapentaenoic Acid (EPA), 174 mg Docosahexaenoic Acid (DHA), 60 mg G

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Participants attend mainstream school.

Exclusion criteria

Exclusion criteria: Children with: 1. Significant neurological problems 2. Psychiatric conditions 3. Any of the following medical problems: 3.1. Epilepsy 3.2. Cerebral palsy 3.3. Multiple sclerosis 3.4. Myalgic encephalopathy 3.5. Pervasive developmental disorder 3.6. Autism 4. Diagnosed ADHD 5. Consumption of essential fatty-acid supplementation within previous three months

Design outcomes

Primary

Measure	Time frame
1. Measurement of change in working memory, confirmed by results from Wechsler Intelligence Scale for Children (WISC-III UK) digit span assessment; time frame: 6 months 2. Measurement of change in reading ability, using the Wechsler Objective Reading Dimensions (WORD) assessment; time frame: 6 months	—

Secondary

Measure	Time frame
1. Measuring a range of behavioural parameters including cognitive problems, hyperactivity, social problems, ADHD and emotional lability as identified by parents using the Conners' Parent Rating Scales-Long Version (CPRS-L); time frame: 6 months 2. Measuring a range of behavioural parameters including cognitive problems, hyperactivity, social problems, ADHD and emotional lability as identified by teachers using the Conners' Teacher Rating Scales-Long Version (CTRS-L); time frame: 6 months	—

Measure

Time frame

1. Measuring a range of behavioural parameters including cognitive problems, hyperactivity, social problems, ADHD and emotional lability as identified by parents using the Conners' Parent Rating Scales-Long Version (CPRS-L); time frame: 6 months 2. Measuring a range of behavioural parameters including cognitive problems, hyperactivity, social problems, ADHD and emotional lability as identified by teachers using the Conners' Teacher Rating Scales-Long Version (CTRS-L); time frame: 6 months

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Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026