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Dedicated Endoscopy for Barrett's Oesophagus (DEBO) compared to current Barrett’s oesophagus surveillance endoscopy practice

A randomised controlled pilot trial comparing current Barrett’s oesophagus surveillance endoscopy practice with a dedicated service

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN12259569
Enrollment
100
Registered
2020-08-12
Start date
2020-10-01
Completion date
Unknown
Last updated
2024-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Barrett's oesophagus Digestive System Barrett's oesophagus

Interventions

The dedicated service will be performed by an upper GI specialist consultant, nurse endoscopist, or clinical research fellow who has a specialist interest in the condition. This is defined by a self-d

Sponsors

Salford Royal NHS Foundation Trust
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Has the capacity to give informed consent 2. Aged >18 years old 3. Diagnosis of non-dysplastic Barrett's oesophagus

Exclusion criteria

Exclusion criteria: 1. Previous diagnosis of precancerous changes 2. Unable to understand written English to a standard at which they can understand the questionnaire

Design outcomes

Primary

MeasureTime frame
Feasibility of a randomised controlled trial comparing a dedicated endoscopy service for Barrett's oesophagus versus current normal practice, measured using health-related quality of life questionnaire completed at 6 weeks post endoscopic surveillance and histological outcomes of endoscopy (no dysplasia, intestinal metaplasia, low-grade dysplasia, or high-grade dysplasia) measured at either the time of dedicated surveillance endoscopy session (intervention arm) or at normally scheduled endoscopy session (control arm)

Secondary

MeasureTime frame
There are no secondary outcome measures

Countries

England, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 7, 2026