Risk of malaria in children aged 5 years or more following seasonal malaria chemoprevention or seasonal vaccination discontinuation

Risk of malaria in children who have reached the age of 5 years and are no longer eligible for seasonal malaria chemoprevention and or seasonal vaccination in Burkina Faso and Mali

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN12207852

Enrollment

5000

Registered

2021-07-02

Start date

2021-07-01

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malaria Infections and Infestations Unspecified malaria

Interventions

The study is built on a large randomised clinical trial investigating whether combining seasonal malaria chemoprevention (SMC) and seasonal vaccination is better than seasonal malaria chemoprevention

Eligibility

Sex/Gender

All

Age

59 Months to 96 Months

Inclusion criteria

Inclusion criteria: 1. Belonging to the seasonal malaria chemoprevention or seasonal vaccination cohort and aged over 59 months 2. Provision of signed informed consent

Exclusion criteria

Exclusion criteria: Absence of informed consent

Design outcomes

Primary

Measure	Time frame
Incidence of uncomplicated malaria or severe malaria in the year after the interventions are stopped measured using patient records	—

Secondary

Measure	Time frame
1. Incidence of asymptomatic malaria parasitemia at the end of the malaria transmission season in the year after the interventions are stopped measured using patient records 2. Incidence of mild or moderate anemia or of malnutrition at the end of the malaria transmission season in the year after the interventions are stopped measured using patient records	—

Countries

Burkina Faso, Mali

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Jun 11, 2026