Rectal cancer suitable for curative R0 resection with or without prior neoadiuvant treatment Cancer Malignant neoplasm of other and ill-defined digestive organs
Conditions
Interventions
The ligation and division of inferior mesenteric artery at its origin from aorta or just beneath the origin of the left colic artery from inferior mesenteric artery during curative R0 resection from r
Sponsors
Szpital Morski [Maritime Hospital ]
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Adult patient with the history of any other neoplasm than rectal and skin cancer 2. Any history of colorectal surgery except the laparoscopic ileostomy in patient awaiting for radical treatment of rectal cancer.
Exclusion criteria
Exclusion criteria: 1. Urgent operation 2. Potentially unresectable disease 3. Comorbid condtions excluding the possibility of standard therapy 4. T4 tumour 5. Any other malignant neoplasm except skin cancer 6. Synchronic distant metastases 7. Lack of patient consent for participation in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Postoperative mortality and morbidity (special reference to the rate of clinical anastomotic leakage) 2. The need for splenic flexure mobilization 3. The number of lymph nodes resected and their pathological estimation 4. Need for blood transfusion 5. Time to disease recurrence 6. Way of spread of disease 7. Cancer related death rate 8. Overall survival | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Permanent stoma rate 2. The rate of stoma reversal 3. Quality of life (QLQ C30 questionnaire) | — |
Countries
Poland
Outcome results
None listed