Morbid obesity Nutritional, Metabolic, Endocrine Morbid obesity
Conditions
Interventions
Morbidity obese patients who are having Roux-en-Y gastric bypass, biliopancreatic deviations with duodenal switch or sleeve gastrectomy are included in the study.
Obese and control group have anthrop
Sponsors
San Carlos Clinical Hospital (Hospital Clínico San Carlos)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Obese participant inclusion criteria: 1. Aged between 18 and 65 years 2. BMI = 40 kg/m2 or = 35 kg/m2 with associated major comorbidities likely to improve after weight loss 3. That morbid obesity is set for at least 5 years. 4. Continuing failures to properly supervised conservative treatments 5. Ability to understand the mechanisms by which weight is lost with surgery and understand that good results are not always achieved 6. Understand that the goal of surgery is not reach the ideal weight 7. Commitment to adhere to the rules of follow-up after surgery 8. Informed consent after receiving all the (oral and written) information Control participant inclusion criteria: 1. Aged between 18 and 65 years 2. No diabetes mellitus (basal glucose 18 kg/m2 4. No drugs or alcohol abuse. 5. No mayor psychiatric disorders (schizophrenia, psychosis) no eating disorders( anorexia nervosa, bulimia) 6. Informed consent after receiving all the (oral and written) information
Exclusion criteria
Exclusion criteria: 1. Endocrine disorders that can cause morbid obesity. 2. Psychological instability including abuse of alcohol or drugs, major psychiatric disorders (schizophrenia, psychosis), mental retardation, eating disorders (bulimia nervosa, binge eating) 3. Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hormonal response after meal test is measured from blood samples taken at baseline, 30, 60, 90 and 120 minutes after ingestion of a standard test meal, at baseline and one year post surgery. | — |
Secondary
| Measure | Time frame |
|---|---|
| Weight loss and the height was measured using an electric scale (SECA®) at baseline, 1, 3 and 5 years. | — |
Countries
Spain
Outcome results
None listed