What are the effects of balance exercises in patients' following total knee replacement ability to perform every day life activities?

What are the effects of enhanced sensori-motor rehabilitation on indices of functional performance associated with patients following total knee replacement?

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN12101643

Enrollment

Registered

2017-03-14

Start date

2012-05-20

Completion date

Unknown

Last updated

2023-05-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis Musculoskeletal Diseases Osteoarthritis

Interventions

After a total knee replacement, participants are randomly allocated to either the intervention rehabilitation group or the control rehabilitation group. Randomisation is done using a computer generate

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Ambulatory patients with osteoarthritis (clinical and radiological findings of advanced osteoarthritis, 6-12 months length of wait for surgery) 2. Undergoing primary standardized cemented total knee replacement by the same surgeon 3. Aged 65-80 years old

Exclusion criteria

Exclusion criteria: 1. Infection, or complications after total knee replacement (TKR) 2. Scheduled for TKR revision surgery 3. Having had any surgery in their lower limbs affecting their gait 4. Cardiovascular diseases, high blood pressure not controlled with medication 5. Neurological/ neuromuscular problems 6. Medical or other musculoskeletal problems that could affect ability to complete objective assessments

Design outcomes

Primary

Measure	Time frame
1. Function is assessed using the Timed Up and Go Test at baseline, eight and 14 weeks post-surgery 2. Pain is measured using Visual Analogue Scale (VAS) at baseline, eight and 14 weeks post-surgery	—

Secondary

Measure	Time frame
1. Balance is measured using Biodex balance system at baseline, eight and 14 weeks post-surgery 2. Knee proprioception is measured using joint position error with a bubble inclinometer at baseline, eight and 14 weeks post-surgery 3. Muscle strength is measured using quadriceps maximum voluntary isometric contraction at 60 degrees of knee flexion with Primus Isokinetic dynamometer at baseline, eight and 14 weeks post-surgery 4. Muscle size is measured using rectus femoris cross sectional area with real time ultrasound at baseline, eight and 14 weeks post-surgery 5. Range of knee motion is measured using a goniometer while the patient is sitting at baseline, eight and 14 weeks post-surgery 6. Peak force of quadriceps with Spike electromyographic EMG during isometric contraction on the dynamometer at baseline, eight and 14 weeks post-surgery 7. Daily living function and quality of life are measured using the Knee injury and Osteoarthritis Outcome Score (KOOS), Knee Outcome Survey: Activities of Daily Living Scale (KOS-ADL )and the Short-Form 12 (SF1-2) at baseline, eight, 14 weeks and two years post-surgery	—

Measure

Time frame

1. Balance is measured using Biodex balance system at baseline, eight and 14 weeks post-surgery 2. Knee proprioception is measured using joint position error with a bubble inclinometer at baseline, eight and 14 weeks post-surgery 3. Muscle strength is measured using quadriceps maximum voluntary isometric contraction at 60 degrees of knee flexion with Primus Isokinetic dynamometer at baseline, eight and 14 weeks post-surgery 4. Muscle size is measured using rectus femoris cross sectional area with real time ultrasound at baseline, eight and 14 weeks post-surgery 5. Range of knee motion is measured using a goniometer while the patient is sitting at baseline, eight and 14 weeks post-surgery 6. Peak force of quadriceps with Spike electromyographic EMG during isometric contraction on the dynamometer at baseline, eight and 14 weeks post-surgery 7. Daily living function and quality of life are measured using the Knee injury and Osteoarthritis Outcome Score (KOOS), Knee Outcome Survey: Activities of Daily Living Scale (KOS-ADL )and the Short-Form 12 (SF1-2) at baseline, eight, 14 weeks and two years post-surgery

—

Countries

Greece

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 3, 2026