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Massage to reduce bilirubin in newborns

Effect of Vimala massage on serum bilirubin levels in late preterm newborns with neonatal jaundice: a randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN12080436
Enrollment
42
Registered
2025-03-25
Start date
2021-07-20
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperbilirubinemia in late premature newborns Neonatal Diseases

Interventions

Randomization was done by random numbers in the Vassar Stata program. Late preterm infants 34 to 36.6 weeks of gestation with hyperbilirubinemia and treatment with phototherapy were randomized to the
they ran their thumbs from the upper lip to the cheeks, then under the ears with the index and middle fingers from the ears to the chin 2. Arms and hands: gently massage the armpit with circular movem
they slid their hands from the shoulder to the wrists
they used twisting motions in the op

Sponsors

Mexican Social Security Institute
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Preterm newborns of 34 to 36.6 weeks of gestation were included according to the Ballard scale 2. On phototherapy for indirect hyperbilirubinemia according to the NICE jaundice guidelines 3. Mother willing to apply the Vimala massage

Exclusion criteria

Exclusion criteria: Neonates with a diagnosis of isoimmunization, inborn errors of metabolism, dehydration or hemodynamic instability or with a mother who withdrew from participating

Design outcomes

Primary

MeasureTime frame
Serum bilirubin was measured on a 0.5 ml blood sample drawn from the dorsal plexus of the hand preferably, at 6:00 a.m. during the 3 days of the study. Bilirubin was measured with non-enzymatic methods using the chemical reaction that uses nitrous oxide to form a colour complex. Total serum bilirubin was determined by adding caffeine benzoate and diazo reagent in the same way as direct bilirubin. Finally, indirect bilirubin was calculated by subtracting total bilirubin minus direct bilirubin.at baseline and on the third day of treatment.

Secondary

MeasureTime frame
1. The number of stools quantified daily by the nursing staff during the 3 days of the study: number of evacuations obtained by the nurse on each shift and recorded on the corresponding vital signs and fluid balance control sheet 2. The number of days of need for phototherapy, considered according to the NICE Guidelines for hyperbilirubinemia 3. The length of hospital stay, including the number of days of hospitalization

Countries

Mexico

Contacts

Public ContactAlma Patricia Gonzalez
alma.gonzalezx@imss.gob.mx+52 (0)4771329126

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026