Treatment of gingival papilla loss for patients diagnosed with periodontal disease Oral Health
Conditions
Interventions
After steps 1 and 2 of periodontal treatment the selected patients will receive the papilla augmentation procedure. The suitable papillae will be injected once with approximately 0.2 ml of hyaluronic
Sponsors
Victor Babe? University of Medicine and Pharmacy Timi?oara
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Nonsmoking, aged above 18 years 2. Presence of an uninterrupted frontal arch (maxillary or mandibular) of teeth affected by severe periodontitis 3. Presence of interproximal pockets deeper than 6 mm in at least 6 adjacent teeth 4. Class I, II, or III papillary recession, according to Nordland and Tarnow's classification (1998) 5. The distance from the contact point to the alveolar bone crest =5 mm 6. Keratinized tissue width of the entire area to be operated of at least 3 mm 7. Good oral hygiene - Plaque Index (PlI<1)
Exclusion criteria
Exclusion criteria: 1. Systemic diseases such as diabetes mellitus, hypertension, or conditions that alter the outcome of periodontal therapy 2. Pregnant or lactating women 3. Tobacco users 4. Patients with known allergies to hyaluronic acid or any excipients of the product used 5. Patients with current or previous drug intake that may predispose to gingival enlargement 6. Patients under orthodontic treatment or having orthodontic treatment in the past 6 months 7. Patients with a history of traumatic oral hygiene measures or periodontal surgeries over the last 6 months in the area of interest
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The presence of new collagen formation and the presence of the hyaluronic acid compound detected using histological analysis after hematoxylin-eosin staining, at 1 week, 2 weeks, and 3 weeks post hyaluronic acid injection recorded dichotomously on the specimens as the presence or absence of the parameter with the following scores: 0/- (absence), 1/+ (presence low), 2/++ (presence medium), 3/+++ (presence high) | — |
Secondary
| Measure | Time frame |
|---|---|
| The presence and characteristics of inflammatory infiltrate, detection of granulomatous reactions, presence of interstitial edema, detected at 1 week, 2 weeks and 3 weeks after hyaluronic injection recorded dichotomously on the specimens as the presence or absence of the parameter with the following scores: 0/- (absence), 1/+ (presence low), 2/++ (presence medium), 3/+++ (presence high) | — |
Countries
Romania
Contacts
Public ContactOctavia-Carolina Vela
Outcome results
None listed