Mild-to-moderate ageing skin signs and skin redness due to cold and wind Not Applicable
Conditions
Interventions
Participants attended clinic visits at screening, baseline and after 14, 28, 56 and 84 days product use (Profhilo Haenkenium®). During the screening visit subjects were informed on study procedures, r
while skin strippings (trough the stratum corneum, superficial layer of the skin) were taken using minimally invasive adhesive foils. The total duration of each visit was 30 minutes. The total study d
Sponsors
IBSA Farmaceutici Italia S.r.l.
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Healthy female subject 2. Caucasian ethnicity 3. Age between 40 and 65 years old 4. Subjects showing mild to moderate ageing skin signs and skin redness due to cold and wind 5. Subjects who have not been recently involved in any other similar study 6. Willingness to use during all the study period only the product to be tested 7. Willingness to not vary the normal daily routine
Exclusion criteria
Exclusion criteria: 1. Subject does not meet the inclusion criteria 2. Positive history for atopy or hypersensitive skin 3. Past history of allergy or sensitivity to cosmetics, toiletries, to solar and/or topical medications 4. Any skin condition that the principal investigator deems inappropriate for participation 5. Pregnancy or nursing women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Antiageing efficacy is measured by means of wrinkle depth and total skin antioxidant capacity using Ferric Reducing Antioxidant Power (FRAP) assay at baseline, and after 14, 28, 56 and 84 days of product use. | — |
Secondary
| Measure | Time frame |
|---|---|
| Skin redness and skin elasticity/compactness assessed using clinical assessment carried out by the dermatologist and the self-assessment carried out by the subjects participating in the study at baseline, and after 14, 28, 56 and 84 days of product use. | — |
Countries
Italy
Outcome results
None listed