Breast cancer after chemotherapy in patients with cognitive impairment Cancer
Conditions
Interventions
The 100 eligible participants are randomly allocated to two different groups:
1. Treatment group: acupuncture will be given at Zusanli (ST 36) Point?Xuhai Point?Tanzhong Point?Zhongwan Point?Qihai (
Sponsors
Beijing Hospital of Traditional Chinese Medicine (TCM)
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Patients with breast cancer at the age of 25 to 55 years old 2. Neuropsychological evidence of cognitive impairment 3. In the 28 months after chemotherapy according to DSM-IV diagnosis of cognitive impairment 4. According to the MoCA score < 26 points, determining with cognitive dysfunction 5. There is a causal relationship between chemotherapy and cognitive impairment, and except for other diseases 6. The type of traditional Chinese medicine is a disorder of qi and blood 7. At least one field of cognitive dysfunction 8. Diagnosis of dementia standard has not yet arrived 9. Have signed informed consent
Exclusion criteria
Exclusion criteria: 1. Because of the depression, thyroid disease, traumatic brain injuries, drug or alcohol poisoning cause cognitive impairment 2. Patients with severe aphasia, depression and mental illness 3. Patients with severe heart, liver, lung, kidney damage caused by cognitive decline and hematopoietic system, endocrine system, severe primary disease 4. Patients can affect the cognitive function of drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Using the Montreal Cognitive Assessment (MoCA)to assess cognitive function. To observe the cognitive ability of patients with breast cancer after chemotherapy with cognitive dysfunction. The outcome measure above will be assessed before the treatment, at 1 month and 2 months during the treatment; the assessments will be repeated at the second and fourth months after the treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Using the Mini-mental State Examination to assess immediate memory, attention, computing power, etc. 2. Using the EORTC QLQ-30 to assess the quality of life. The outcome measures above will be assessed before the treatment, at 1 month and 2 months during the treatment; the assessments will be repeated at the second and fourth months after the treatment. 3. Safety assessment. Acupuncture treatment can lead to curved needle, needle breakage and adverse reactions such as subcutaneous hematoma, therefore we will evaluate the safety of acupuncture. | — |
Countries
China
Outcome results
None listed