Acceptance and commitment therapy (ACT) for treatment-resistant panic disorder with agoraphobia

What to do when the gold standard fails? A randomised controlled trial of acceptance and commitment therapy (ACT) for treatment resistant patients diagnosed with panic disorder with agoraphobia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN12042066

Enrollment

Registered

2010-07-26

Start date

2010-07-12

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Panic disorder/agoraphobia Mental and Behavioural Disorders Phobic anxiety disorders

Interventions

1. Acceptance and commitment therapy (ACT), administered twice weekly over four weeks for a total of 8 sessions. Each session will range between 60 - 120 minutes. 2. Waitlist control, total duration o

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 18 - 65 years, either sex 2. Diagnosis of panic disorder (PD) and/or agoraphobia (AG) 3. Either Mobility Inventory greater than or equal to 1.5 or Clinical Global Interview greater than or equal to 4 4. Informed consent 5. Completed an adequate course of psychological or pharmacological treatment (Added 11/08/2011)

Exclusion criteria

Exclusion criteria: 1. Acute suicidality 2. Bipolar disorder 3. Any psychotic disorder 4. Any eating disorder 5. Acute alcohol/drug dependency 6. Current psychological treatment

Design outcomes

Primary

Measure	Time frame
Measured pre-, post-, and 6-month follow up: 1. Mobility Inventory 2. Clinical Global Interview 3. Panic Agoraphobia Scale 4. Acceptance and Commitment Questionnaire-II	—

Secondary

Measure	Time frame
Measured pre-, post-, and 6-month follow up: 1. Personal Values Questionnaire 2. Anxiety Sensitivity Index 3. Agoraphobic Cognitions Questionnaire 4. Body Symptoms Questionnaire	—

Countries

Germany

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026