Effects of subfascial infiltration of 0.25% bupivacaine versus N/saline in elective abdominal surgery: a randomised controlled trial.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN12037208

Enrollment

Registered

2004-09-30

Start date

2003-05-30

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Signs and Symptoms: Post-operative pain Signs and Symptoms Post-operative pain

Interventions

Patients will undergo a simple non-invasive pulmonary function test carried out at the patients bedside and repeated each morning for the first 7 days postoperatively. Added August 2008: trial stoppe

Eligibility

Inclusion criteria

Inclusion criteria: All patients who require abdominal surgery (midline laparotomy) and are aged between 18-90 will be entered into the study excluding the following: History of drug abuse, chronic pain, regular medication with opioids/non-steroidal anti-inflammatory drugs (NSAIDs), diabetes, morbid obesity, unable to use patient controlled analgesia (PCA). A total of 80 patients will be studied, 40 in each group (those receiving a placebo, and those receiving 0.25% bupivacaine).

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

Measure	Time frame
Surgery pain scores.	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026