Does antithrombotic prophylaxis increase the incidence of post-operative bleeding and duration of post-operative hospital stay after thyroidectomy? A retrospective study

Does antithrombotic prophylaxis worsen early outcome of total thyroidectomy? A retrospective cohort study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN12029395

Enrollment

526

Registered

2018-02-05

Start date

2013-02-01

Completion date

Unknown

Last updated

2019-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

factors influencing outcome of thyroid surgery Surgery thyroid surgery

Interventions

Participants have antithrombotic prophylaxis with low-molecular-weight heparin (a subcutaneous prophylactic dose (i.e., 0.3 ml) of nadroparin calcium administered the day before their operation and co

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All patients submitted to total thyroidectomy for whom antithrombotic prophylaxis would be indicated.

Exclusion criteria

Exclusion criteria: 1. Aged below 18 years 2. Anticoagulant or antiplatelet therapy 3. Recurrent goitre and operations other than total thyroidectomy (hemithyroidectomy, thyroidectomy with central or lateral neck dissection).

Design outcomes

Primary

Measure	Time frame
1. Incidence of severe postoperative cervical hematoma is measured using the the need for surgical revision 2. Length of postoperative hospital stay is measured using patient records at discharge	—

Secondary

Measure	Time frame
Incidence of thromboembolic events is measured using the diagnosis of deep vein thrombosis and/or pulmonary embolism.	—

Countries

Italy

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 21, 2026