Clinical evaluation of the effects of paediatric dental general anaesthesia and midazolam sedation on cognitive function, anxiety and access to future dental care

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN12026431

Enrollment

200

Registered

2005-10-05

Start date

2004-01-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental caries requiring multiple extractions Oral Health Caries

Interventions

1. General anaesthesia due to child's inability to cope whilst conscious 2. Midazolam versus placebo to reduce pre-operative anxiety

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Children aged 5-10 years having multiple dental extractions under general anaesthesia due to their inability to cope with conscious sedation.

Exclusion criteria

Exclusion criteria: 1. English not first language 2. Learning disability 3. Neurological disorder 4. Psychiatric disorder 5. Respiratory disorder

Design outcomes

Primary

Measure	Time frame
1. Cognitive function postoperatively 2. Anxiety pre-operatively 3. Interaction between general anaesthesia and midazolam	—

Secondary

Measure	Time frame
Future dental attendance patterns.	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026