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The influence of body composition on liver cancer patients undergoing surgery

Do low skeletal muscle bulk and disturbed body fat mass impact tumor recurrence in stage I/II hepatocellular carcinoma undergoing surgery?

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN12021668
Enrollment
600
Registered
2024-05-01
Start date
2012-02-01
Completion date
Unknown
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular carcinoma Cancer

Interventions

For preoperative tumor staging, all patients recruited will undergo computed tomography (CT) scans no more than 1 month before liver resection. Parameters of body composition will be acquired from non

Sponsors

Linkou Chang Gung Memorial Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Stage I and II HCC patients who received curative liver resection at Linkou Chang Gung Memorial Hospital (CGMH) 2. Patients without cancer who received abdominal CT at Linkou Chang Gung Memorial Hospital (CGMH)

Exclusion criteria

Exclusion criteria: 1. Patients who lacked critical clinical data or image 2. Received concomitant extra-hepatic surgery except for cholecystectomy 3. Underwent intra-operative vascular/biliary reconstruction 4. History of major operations or trauma within 3 months of liver surgery

Design outcomes

Primary

MeasureTime frame
Disease-free survival is calculated from the date of surgery to the date of the first documented clinical disease recurrence and is estimated by Kaplan-Meier survival analysis

Secondary

MeasureTime frame
1. Early tumor recurrence, defined as recurrence of the tumor within 2 years of surgery 2. Overall tumor recurrence, defined as the occurrence of the tumor after surgery, measured in years

Countries

Taiwan

Contacts

Public ContactChao-Wei Lee
yjding@cgmh.org.tw+886 (0)975366192

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026