Strongyloides stercoralis infection Infections and Infestations Strongyloides stercoralis infection
Conditions
Interventions
Subjects will be randomly assigned to one of the two treatment arms:
Group 1: Participants receive a single dose of ivermectin 200 ug/kg.
Group 2: Participants receive
Sponsors
Swiss Tropical and Public Health Institute (Swiss TPH)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged 18 years or over 2. Infected with S. stercoralis infection 3. Absence of major systemic illnesses 4. Written informed consent signed
Exclusion criteria
Exclusion criteria: 1. Abnormal medical conditions or chronic disease 2. Negative diagnostic result for soil-transmitted helminthes infection 3. No written informed consent 4. Recent anthelminthic treatment (past 2 months) 5. Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Strongyloides stercoralis infection status is determined 21 days after treatment using the Baermann method in 2 stool samples. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Adverse events are measured through self-reporting 3, 24, 48 and 72 hours after treatment 2. S. stercoralis infection intensity is measured using a larval count in stool samples 21 days after treatment in relation to baseline infection intensity (LRR) 3. O. viverrini and other helminth infection status and intensity is measured using stool samples (Kato Katz method) 21 days after treatment | — |
Countries
Laos
Outcome results
None listed