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Comparing the effect of two different grafts, one derived from the palate and the other from the patient's blood, on the improvement of gum tissue thickness around dental implants

Comparison of platelet-rich fibrin and sub-epithelial connective tissue graft in managing thin gingival biotype surrounding acid-etched titanium implants

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN11961919
Enrollment
10
Registered
2021-10-09
Start date
2017-04-04
Completion date
Unknown
Last updated
2023-11-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peri-implant soft tissue repair Oral Health

Interventions

The present study was a split-mouth controlled clinical trial. For each study participant, one site was treated with SCTG while the other was treated with PRF membrane during dental i

Sponsors

Mansoura University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Bilateral missing teeth in the maxillary anterior and premolar area 2. Facial thin gingival phenotype facially (i.e. ?1.5 mm) as evaluated using cone-beam computed tomography (CBCT) (Claffey and Shanley 1986) 3. Bilateral edentulous sites dimension of at least 5.5mm bucco-lingually, 5.5mm mesio-distally, and with a minimal bone height of 8 mm 4. Teeth adjacent to the selected edentulous site must be free of periodontal disease involvement 5. Adjacent teeth permit occlusal guidance 6. An opposing dentition to the edentulous area with teeth, implants or fixed prosthesis

Exclusion criteria

Exclusion criteria: 1. Untreated rampant caries and/or uncontrolled periodontal disease 2. Insufficient inter-occlusal distance for implant placement and restoration 3. Smokers 4. Systemic diseases contraindicating the dental implant placement like osteoporosis and uncontrolled diabetes mellitus 5. History of radiation in the head and neck region 6. Pregnancy 7. Uncooperative patient

Design outcomes

Primary

MeasureTime frame
Change in peri-implant soft tissue thickness measured using cone-beam computed tomography (CBCT) at the baseline (T0) and 6 months postoperatively (T1)

Secondary

MeasureTime frame
Esthetic improvement measured using the Pink esthetic score (PES) at T1 and 3 months later after prosthesis placement (T2)

Countries

Egypt

Contacts

Public ContactIslam Ateia
dentfac@mans.edu.eg+20 (0)1002772832

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 10, 2026