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Aerobic exercise to achieve a higher cerebral blood flow

Utilizing nasal breathing during aerobic exercise is associated with a higher cerebral blood flow volume

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN11953452
Enrollment
22
Registered
2026-07-01
Start date
2023-03-23
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebrovascular hemodynamics in healthy young males Circulatory System

Interventions

This randomized controlled trial investigates the acute hemodynamic and cerebrovascular adaptations to nasal breathing during aerobic exercise following a 4-week training intervention. Participants ar

Sponsors

Baylor University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 30 Years

Inclusion criteria

Inclusion criteria: 1. Male individuals between 18 and 30 years of age 2. No orthopedic limitations or any recent surgery during the past 2 years that would limit participation in the study 3. No absolute or relative contraindications for exercise testing or prescription as outlined by the American College of Sports Medicine 4. On no medications or receiving treatment for any cardiopulmonary disease 5. Not taking any medication that affects blood pressure and/or heart rate

Exclusion criteria

Exclusion criteria: 1. Females 2. Males outside of the age range 3. Pre-existing cardiometabolic conditions

Design outcomes

Primary

MeasureTime frame
Cerebral blood flow measured using ultrasound sonography during GXT (visit 1 and visit 2), calculating volumetric CBF during peak systolic and diastolic phases in the internal and external carotid artery, at baseline (V1) and at the end of the intervention (following 4 weeks of the intervention, V2)

Secondary

MeasureTime frame
Cardiac limitation measured using oxygen pulse (O2pulse, ml/beat), calculated by dividing oxygen uptake (V?O2, mL·min-1) by HR (bpm), which is an analogous estimate of stroke volume, at baseline (V1) and at the end of the intervention (following 4 weeks of the intervention, V2)

Countries

United States of America

Contacts

Public ContactJose Moris
jose.moris@tamiu.edu+1 (0)956 326 3288

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Jul 23, 2026