Cerebrovascular hemodynamics in healthy young males Circulatory System
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Male individuals between 18 and 30 years of age 2. No orthopedic limitations or any recent surgery during the past 2 years that would limit participation in the study 3. No absolute or relative contraindications for exercise testing or prescription as outlined by the American College of Sports Medicine 4. On no medications or receiving treatment for any cardiopulmonary disease 5. Not taking any medication that affects blood pressure and/or heart rate
Exclusion criteria
Exclusion criteria: 1. Females 2. Males outside of the age range 3. Pre-existing cardiometabolic conditions
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cerebral blood flow measured using ultrasound sonography during GXT (visit 1 and visit 2), calculating volumetric CBF during peak systolic and diastolic phases in the internal and external carotid artery, at baseline (V1) and at the end of the intervention (following 4 weeks of the intervention, V2) | — |
Secondary
| Measure | Time frame |
|---|---|
| Cardiac limitation measured using oxygen pulse (O2pulse, ml/beat), calculated by dividing oxygen uptake (V?O2, mL·min-1) by HR (bpm), which is an analogous estimate of stroke volume, at baseline (V1) and at the end of the intervention (following 4 weeks of the intervention, V2) | — |
Countries
United States of America