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Effects of thoracic analgesia on gastrointestinal motility

Gastrointestinal motility following thoracic surgery, the effect of thoracic epidural analgesia: a randomised controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN11953159
Enrollment
30
Registered
2017-03-20
Start date
2002-03-20
Completion date
Unknown
Last updated
2017-11-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastrointestinal motility after major thoracic surgery Digestive System Gastrointestinal motility after major thoracic surgery

Interventions

All patients have a standard preoperative assessment and received teaching on how to score pain and to report side effects. In addition, they are informed about postoperative tests, feeding and early

Sponsors

University Hospital of Heraklion
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Undergoing major thoracic surgery 2. Age 30-85 years

Exclusion criteria

Exclusion criteria: 1. Diabetes mellitus 2. ASA physical status >III 3. History of chronic pain 4. Drug/alcohol dependance 5. Treatment with drugs known to affect GI motility 6. Inflammatory bowel disease 7. Previous bowel surgery 8. Morphine or local anaesthetic allergy 8. History of abdominal radiation 9. Contraindications to insertion of an epidural catheter 10. Severe renal or hepatic disease

Design outcomes

Primary

MeasureTime frame
1. Oroceacal transit time is assessed using the lactulose H2 test on post-operative days 1 and 3 2. Colonic transit time is assessed by radiopaque markers and abdominal X-rays on post-operative day 4

Secondary

MeasureTime frame
Pain is measured using a visual analogue scale (VAS) on post-operative days 1 and 3

Countries

Greece

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026