Gastrointestinal motility after major thoracic surgery Digestive System Gastrointestinal motility after major thoracic surgery
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Undergoing major thoracic surgery 2. Age 30-85 years
Exclusion criteria
Exclusion criteria: 1. Diabetes mellitus 2. ASA physical status >III 3. History of chronic pain 4. Drug/alcohol dependance 5. Treatment with drugs known to affect GI motility 6. Inflammatory bowel disease 7. Previous bowel surgery 8. Morphine or local anaesthetic allergy 8. History of abdominal radiation 9. Contraindications to insertion of an epidural catheter 10. Severe renal or hepatic disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Oroceacal transit time is assessed using the lactulose H2 test on post-operative days 1 and 3 2. Colonic transit time is assessed by radiopaque markers and abdominal X-rays on post-operative day 4 | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain is measured using a visual analogue scale (VAS) on post-operative days 1 and 3 | — |
Countries
Greece