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The effects of transcranial cerebellar electrical stimulation on symptoms in Friedreich ataxia

Dentato-thalamo-cortical tracts in Friedreich ataxia: impact of its modulation on Friedreich ataxia symptoms and brain functional architecture

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN11920565
Enrollment
25
Registered
2023-01-16
Start date
2021-09-01
Completion date
Unknown
Last updated
2023-06-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Friedreich ataxia Nervous System Diseases

Interventions

The function Randperm (2) in the Matlab program will be used to allocate the subjects either to the intervention first and the sham intervention second or the other way around. Participating Friedreic

Sponsors

HUB-Hôpital Erasme, Université Libre de Bruxelles
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Clinically confirmed Friedreich ataxia

Exclusion criteria

Exclusion criteria: Other comorbid neurological diseases

Design outcomes

Primary

MeasureTime frame
1. Impairments in cerebellar ataxia measured using the Scale for the Assessment and Rating of Ataxia (SARA) before and after intervention 2. Assessment of cerebellar ataxia measured using the Composite Cerebellar Functional Severity Score (CCFS) before and after intervention 3. Cerebellar cognitive affective syndrome measured using the Cerebellar Cognitive Affective Score (CCAS) before and after intervention—

Secondary

MeasureTime frame
Somatosensory cortices evoked response to a tactile oddball paradigm measured using functional magnetic resonance imaging (fMRI) before and after intervention—

Countries

Belgium

Contacts

Public ContactGilles Naeije
gilles.naeije@erasme.ulb.ac.be+3225558196

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026