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The effects of consuming melted cheese and grass-fed cheese on markers of metabolic health

A randomized control trial to investigate the impact of long-term consumption of melted cheddar, and to examine the effect of grass-fed vs total mixed ration (TMR) cheddar, on markers of metabolic health

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN11913510
Enrollment
320
Registered
2021-03-16
Start date
2020-01-16
Completion date
Unknown
Last updated
2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blood lipids Nutritional, Metabolic, Endocrine

Interventions

In this parallel, multi-arm study examining the effect of the intervention over 6 weeks, participants will consume one of the following diet treatments per day
1. 120 g solid cheddar (non-melted), 100% pasture-fed cheddar 2. 120 g melted, 100% pasture-fed cheddar (test) 3. ‘Deconstructed cheese’ (49 g butter, 30 g calcium case

Sponsors

Food for Health Ireland
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Current participant inclusion criteria as of 18/05/2022: 1. Healthy, not taking medication for cholesterol, blood pressure or digestion 2. Not following a prescribed diet for any reason (weight loss, cholesterol etc) 3. Free from dairy intolerance/allergy and consume an omnivorous diet 4. Male or female, aged =50 years 5. BMI >25 kg/m² Previous participant inclusion criteria: 1. Healthy, not taking medication for cholesterol, blood pressure or digestion 2. Not following a prescribed diet for any reason (weight loss, cholesterol etc) 3. Free from dairy intolerance/allergy and consume an omnivorous diet 4. Male or female, aged between 50– 69 years 5. BMI >25 kg/m²

Exclusion criteria

Exclusion criteria: Current participant exclusion criteria as of 18/05/2022: 1. Taking medication for cholesterol, blood pressure, or digestion 2. Following a prescribed diet for any reason (weight loss, cholesterol, etc) 3. Dairy intolerance/allergy and consuming an omnivorous diet 4. Male or female, aged 70 years to be excluded as a COVID-19 precaution

Design outcomes

Primary

MeasureTime frame
Blood lipids measured with the HORIBA Pentra C400 from fasted blood samples collected at baseline and after the 6-week intervention period

Secondary

MeasureTime frame
Blood glucose and inflammatory markers measured with the HORIBA Pentra C400 from fasted blood samples collected at baseline and after the 6-week intervention period

Countries

Ireland

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026