Vasa praevia and abnormal umbilical cord insertion Pregnancy and Childbirth Fetus and newborn affected by other and unspecified conditions of umbilical cord
Conditions
Interventions
This is a retrospective cohort study undertaken at the Fetal Medicine Unit at a large maternity unit in United Kingdom. This unit routinely offers women an appointment at 11-13 weeks’ gestation for da
Sponsors
Medway NHS Foundation Trust
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Singleton pregnancies which booked and delivered at our hospital during the study period 2. Delivered phenotypically normal neonates at = 24 weeks’ gestation
Exclusion criteria
Exclusion criteria: Multiple pregnancies, miscarriages, terminations of pregnancy, those with major fetal defects and those that were lost to follow-up
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stillbirth and perinatal mortality rate during the study period assessed in the standardised rate i.e. per 1,000 livebirths and as n (%). Data collected will be based on retrospective search of electronic databases. These will be compared between cases and controls and data will be presented as rates as well as odds ratios (95% confidence intervals) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. The prevalence of vasa praevia, determined by the number of cases of vasa praevia during the study period divided by the total number of pregnancies delivered > 24 weeks during the study period 2. The maternal and pregnancy risk factors associated with vasa praevia. At every booking visit, maternal demographic factors (e.g. age, weight, height, racial origin, method of conception etc) are recorded for every pregnancy. Likewise, there are pregnancy risks factors such as medical conditions, pregnancy complications that are recorded for every pregnancy in the study period. The researchers will compare these in pregnancies with vasa praevia to those without vasa praevia during the study period. | — |
Countries
United Kingdom
Outcome results
None listed