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Improvement in cryptococcosis diagnosis among HIV-infected patients in Mozambique

Re-introduction of India ink microscopy testing as a low-cost laboratory diagnostic for cryptococcosis among HIV-infected patients in Southern Mozambique: An implementation research protocol

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN11882960
Enrollment
98
Registered
2024-08-06
Start date
2024-09-01
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Re-introduction of India ink microscopy testing as a low-cost laboratory diagnostic for cryptococcosis among HIV-infected patients Infections and Infestations

Interventions

Following completion of the pre-implementation phase assessments and local stakeholder adaptation meetings, each study facility will roll out India Ink microscopy for cryptococcosis diagnosis as per t

Sponsors

Tulane University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Healthcare providers: clinicians attending adult HIV-infected patients in screening or consultation rooms and laboratory technicians

Exclusion criteria

Exclusion criteria: 1. Clinicians attending to pediatric patients 2. Clinicians who are not engaged in HIV/AIDS care and treatment 3. Laboratory technicians who are not engaged in laboratory diagnostic testing for cryptococcosis

Design outcomes

Primary

MeasureTime frame
Increase opportunity for screening of adult HIV-infected patients suspected of having a cryptococcal disease in study sites measured using microscopy testing with India Ink at one time point

Secondary

MeasureTime frame
1. Empirical treatment practice time among clinicians managing cryptococcal infections measured using record keeping during the sample and information flow 2. Clinician satisfaction with the availability of the tool for clinical decision support measured using an in-depth interview record and a 5-point Likert scale at 9 months of the adaptation-intervention period (the end of the intervention phase)

Countries

Mozambique

Contacts

Public ContactJose Langa
josecarloslanga@yahoo.com.br+258 847301265

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Jul 23, 2026