A study to help identify depression in patients aged 65 years and older who are registered with a GP in the North of England

Case finding for depression in primary care: a regression discontinuity design CASCADE study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN11841241

Enrollment

2089

Registered

2022-10-27

Start date

2022-09-22

Completion date

Unknown

Last updated

2025-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression Mental and Behavioural Disorders

Interventions

Participants will complete the GDS at baseline and post the questionnaire back to the York Trials Unit (YTU), University of York. Members of the research team at YTU will score the GDS and if the sco

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 65 years and over 2. Community-dwelling 3. Based in the North of England 4. Willing and able to provide consent

Exclusion criteria

Exclusion criteria: 1. Currently have a diagnosis of depression 2. Currently receiving or waiting for treatment for depression 3. Do not consent to their GP being contracted by the research team about physical or mental health concerns

Design outcomes

Primary

Measure	Time frame
Symptoms of low mood and depression measured using the Geriatric Depression Scale (GDS) at baseline and 6 months	—

Secondary

Measure	Time frame
1. Health-related quality of life measured by the EQ-5D-5L at baseline and 6 months 2. Health service resource use with a specific focus on mental health services, including NHS and private care, use of medications, and self-care at 6 months 3. Acceptability of the intervention to patients and care providers, and if and how screening could be incorporated in practice, assessed using interviews during the recruitment and follow-up stages of the study	—

Measure

Time frame

1. Health-related quality of life measured by the EQ-5D-5L at baseline and 6 months 2. Health service resource use with a specific focus on mental health services, including NHS and private care, use of medications, and self-care at 6 months 3. Acceptability of the intervention to patients and care providers, and if and how screening could be incorporated in practice, assessed using interviews during the recruitment and follow-up stages of the study

—

Countries

England, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026