Evaluation of colon cancer screening on colon cancer mortality

Impact of population screening on colorectal cancer mortality: a natural experiment

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN11768442

Enrollment

46000000

Registered

2019-02-05

Start date

2019-01-10

Completion date

Unknown

Last updated

2020-12-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer Cancer Malignant neoplasm of colon

Interventions

The present study is an ecological analysis of colorectal cancer-specific deaths at a province level. We compare age-standardised mortality rates in provinces that were exposed to screening with provi

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The entire population of Spain

Exclusion criteria

Exclusion criteria: Resident of Spanish provinces that started screening after 2009.

Design outcomes

Primary

Measure	Time frame
Current primary outcome measure as of 25/02/2019: Mortality rates will be measured using the biannual CRC-specific 1999 age-standardised mortality rates (measured by the National Statistical Office of Spain) for the population aged 50-69 years old. Previous primary outcome measure: Mortality rates will be measured using the biannual CRC-specific 1999 age-standardised mortality rates (measured by the National Statistical Office of Spain) for the population aged 50-79 years old.	—

Measure

Time frame

Current primary outcome measure as of 25/02/2019: Mortality rates will be measured using the biannual CRC-specific 1999 age-standardised mortality rates (measured by the National Statistical Office of Spain) for the population aged 50-69 years old. Previous primary outcome measure: Mortality rates will be measured using the biannual CRC-specific 1999 age-standardised mortality rates (measured by the National Statistical Office of Spain) for the population aged 50-79 years old.

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Secondary

Measure	Time frame
1. Biannual CRC-specific 1999 Age-standardised mortality rates for overall population, measured by the National Statistical Office of Spain (INE) 2. Biannual CRC-specific 1999 Age-standardised mortality rates for population aged between 40 to 49 years old, measured by the National Statistical Office of Spain (INE) 3. Biannual CRC-specific 1999 Age-standardised mortality rates for population aged between 0 to 39 years old, measured by the National Statistical Office of Spain (INE)	—

Measure

Time frame

1. Biannual CRC-specific 1999 Age-standardised mortality rates for overall population, measured by the National Statistical Office of Spain (INE) 2. Biannual CRC-specific 1999 Age-standardised mortality rates for population aged between 40 to 49 years old, measured by the National Statistical Office of Spain (INE) 3. Biannual CRC-specific 1999 Age-standardised mortality rates for population aged between 0 to 39 years old, measured by the National Statistical Office of Spain (INE)

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Countries

Spain

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026