Limitations of motor brain activity – use of virtual reality for simulation of therapeutic interventions

Pre-Action Games and Exercises: Utility of virtual reality as supplemental stroke survivor rehabilitation in stroke and/or traumatic brain injury survivors to examine change in functional motor performance and volumetric cortical grey matter

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN11757651

Enrollment

Registered

2019-08-01

Start date

2015-01-10

Completion date

Unknown

Last updated

2020-09-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic stroke and traumatic brain injury Nervous System Diseases

Interventions

The intervention included traditional physical and occupational therapy and controlling virtual limbs to simulate unimpaired physical movement. The subjects were divided into three gr

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Stroke survivors 2. Traumatic brain injury survivors 3. Actively engaged in physical and occupational therapy 4. Age range: 21 years and older 5. Gender: male or female

Exclusion criteria

Exclusion criteria: 1. Patients unable to comprehend use of standard computer mouse to point to and control virtual limbs

Design outcomes

Primary

Measure	Time frame
Measured at baseline (1-3 days before intervention) and post-intervention (10-weeks). 1. Changes in cortical grey matter volume measured using MRI data analyzed using voxel-based morphometry and correlated with quantified motor skills 2. Motor skills evaluated by muscle strength (hand key pinch strength, grasp and three-jaw pinch) and active range of motion (AROM) of shoulder, elbow, and wrist	—

Countries

Czech Republic

Contacts

Public ContactVincent Macri

vjm@vincemacri.us603-502-6068

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 17, 2026