How migration affects health during childbirth and anesthesia: a study

Understanding the healthy migrant effect in the context of anaesthetic and perinatal challenges: an ambispective observational study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN11740283

Enrollment

5000

Registered

2024-09-25

Start date

2023-01-01

Completion date

Unknown

Last updated

2024-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy-migrant effect or migrant health paradox Not Applicable

Interventions

An ambispective observational study will be used including both a retrospective chart review and a prospective study design in order to compare perinatal, maternal and neonatal outcomes among refugee

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. We will include internationally recently migrated pregnant women with a length of stay in Greece =3 years, giving birth in Athens and women of Greek origin. 2. All births from 22+0 weeks’ gestation or from infants weighing =500 g during the study period.

Exclusion criteria

Exclusion criteria: Pregnant women with incomplete data in the hospital registry database or those referred to another center due to maternal or infant issues

Design outcomes

Primary

Measure	Time frame
Measured by retrospective chart review: 1. Maternal pathology: Maternal comorbidities will include Gestational Diabetes Mellitus (GDM), hypertensive disorders (preeclampsia/eclampsia), smoking during pregnancy, HIV, hepatitis, anaemia and other health problems. 2. Anaesthetic data: General/CSE/spinal for caesarean delivery, epidural analgesia during labor 3. Maternal and neonatal outcomes: 3.1. Maternal outcomes will include postpartum haemorrhage, maternal transfusion, mother requiring HDU/ICU admission. 3.2. Neonatal outcomes will include 5-minute Apgar score <7, stillbirth rates, preterm birth (=37weeks), intrauterine growth retardation (IUGR), emergency intubation of the newborn in OR, meconium-stained amniotic fluid, congenital abnormalities, Neonatal Intensive Care Unit admission/Special Care Baby Unit admission/Ward, perinatal mortality	—

Measure

Time frame

Measured by retrospective chart review: 1. Maternal pathology: Maternal comorbidities will include Gestational Diabetes Mellitus (GDM), hypertensive disorders (preeclampsia/eclampsia), smoking during pregnancy, HIV, hepatitis, anaemia and other health problems. 2. Anaesthetic data: General/CSE/spinal for caesarean delivery, epidural analgesia during labor 3. Maternal and neonatal outcomes: 3.1. Maternal outcomes will include postpartum haemorrhage, maternal transfusion, mother requiring HDU/ICU admission. 3.2. Neonatal outcomes will include 5-minute Apgar score <7, stillbirth rates, preterm birth (=37weeks), intrauterine growth retardation (IUGR), emergency intubation of the newborn in OR, meconium-stained amniotic fluid, congenital abnormalities, Neonatal Intensive Care Unit admission/Special Care Baby Unit admission/Ward, perinatal mortality

—

Secondary

Measure	Time frame
Measured by retrospective chart review: 1. Provision of neuraxial anaesthesia during labour 2. Overall maternal satisfaction	—

Countries

Greece

Contacts

Public ContactKonstantIna KalopIta

ntikal@hotmail.com+30 6944353918

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026