Urologic tumors (kidney, prostate, bladder, penis) Cancer
Conditions
Interventions
A comparison between nuclear imaging (PET/CT scan) pictures and surgical pathology in patients with different neoplasms undergoing surgical excision.
Sponsors
Ospedale Civile "Spirito Santo"
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Subject aged over 18 at diagnosis 2. Subject with renal or bladder or prostate or penile cancer waiting for surgical excision or imaging restaging due to progressive disease 3. Availability of already done cross-sectional imaging in the last month 4. Karnofsky index >80% 5. Absence of relevant comorbidities (see exclusion criteria) 6. Full mental ability to understand the value and the relevance of the protocol and the related procedures showed in the “Informativa per il soggetto” 7. Full mental ability in order to give informed consent 8. Negative pregnancy test for women potentially at risk for pregnancies
Exclusion criteria
Exclusion criteria: 1. Hb levels < 10 gr/dL 2. Presence of copper metabolism diseases (Menkes or Wilson diseases) 3. Previous participation in clinical trial involving ionizing radiation for diagnostic or therapeutic finality in the last year 4. Working exposition to ionizing radiation 5. Each condition that could alter and reduce the compliance of the subject to the participation to the study protocol 6. Mental inability to fully understand the “Informativa per il soggetto”
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity and specificity based on whole body PET/CT after 64CuCL2 in primitive and metastatic lesions, measured immediately (1-2 days) after the PET/CT scan | — |
Secondary
| Measure | Time frame |
|---|---|
| 64CuCL2 PET/CT technique performance in target/background contrast (T/B), measured immediately (1-2 days) after the PET/CT scan | — |
Countries
Italy
Outcome results
None listed