Reduction of postprandial glycaemia Nutritional, Metabolic, Endocrine
Conditions
Interventions
The study is conducted using a counterbalanced crossover trial design, with each participant acting as their own control. Participants will attend the lab on four separate occasions, separated by at l
Sponsors
Wild Blueberry Association of North America
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Between 18 – 56 years of age 2. Body mass index (BMI) <27.0 kg/m2 3. Be in general good health (with no known food allergies/intolerances) 4. Not taking any medication/s known to affect blood pressure, blood glucose (like diabetic medication) or cholesterol 5. Not be pregnant or planning a pregnancy within the next 3 months. Not have been pregnant or lactating within the previous 6 months 6. Not menopausal 7. Like all the study foods and test products (checked at screening) 8. Be a non-smoker (for at least the last 6 months) 9. Sufficient fluency in the English language to be able to understand the study instructions and questionnaires 10. Willing to visit the laboratory for a screening session (1 hour) and 4 test mornings (8.00 am – 12.00 pm)
Exclusion criteria
Exclusion criteria: 1. Age =56 years 2. BMI >27 kg/m2 3. Blood donation 14 units/week of alcohol in women or >21 units/week in men in the last 3 months 6. For women: pregnancy, lactation, perimenopause 7. No access to mobile phone and internet 8. Simultaneous participation in other relevant studies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Interstitial glucose measured by continuous glucose monitoring at baseline and every 15 minutes across a 3-hour postprandial period | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Blood pressure measured using an automatic blood pressure monitor at baseline and every 30 minutes 2. Appetite measured using visual analogue scales at baseline and every 30 minutes 3. Incretin hormones measured using venous blood samples from cannulation at baseline and every 30 minutes 4. Cognitive function measured using the Visual Verbal Learning test (VVLT), Corsi Block tapping test (Corsi) and the Rapid Visual Information Processing task (RVIP) at baseline and at 90 minutes after consumption of the drink | — |
Countries
England, United Kingdom
Contacts
Public ContactLucy Ellis
Outcome results
None listed