Antenatal anxiety and depression Mental and Behavioural Disorders Antenatal anxiety and depression
Conditions
Interventions
Participants will be randomly assigned following simple randomization procedures to 1 of 2 conditions. The randomization sequence will be created using R-studio with a 1:1 allocation.
Sponsors
Goldsmiths, University of London
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Mother inclusion criteria: 1. Have a computer or a smart phone at home 2. Referred by the clinical team 3. Fluent in English 4. Aged 18-45 years old 5. Singleton birth Infant inclusion criteria: 1. Born after 37 weeks 2. Age 6 months 3. No major disability or medical disorder
Exclusion criteria
Exclusion criteria: Mother exclusion criteria: 1. Not enough time to dedicate to the study 2. Serious medical disorder, psychosis, bipolar disorder or drug abuse 3. If the baby is born before 37 weeks, is still born, or the mother has a miscarriage the mother will not be included in the study will be discontinued Infant exclusion criteria: 1. Any medical disorder or major disability 2. Born before 37 weeks
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Depression is assessed using the Edinburgh Postnatal Depression Scale (EPDS) at 20 , 26 and 32 weeks, and 1, 3 and 6 months postnatal 2. Anxiety is assessed using the Spielberger State and Trait Anxiety (STAI) at 20 , 26 and 32 weeks, and 1, 3 and 6 months postnatal and the Pregnancy-Related Anxiety Questionnaire Revised (PRAQ-R2) at 20, 26 and 32 weeks 3. Stress is assessed using the Perceived Stress Scale (PSS) at 20 , 26 and 32 weeks, and 1, 3 and 6 months postnatal | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Mother-infant attachment is assessed using the Mother Infant Bonding Scale (MIBS) at 1 and 3 months postnatal, the Maternal Antenatal Attachment Scale (MAAS) at 20, 26 and 32 weeks and the Maternal Postnatal Attachment Scale (MPAS) at 1, 3 and 6 months postnatal 2. Infant cognitive and behavioural development is assessed using the Infant Behaviour Questionnaire revised (IBQ-R) and the Bayley Scales of Infant and Toddler Development (Bayley III) at when the child is 6 months old 3. Biological changes in cortisol and various cytokines are measured using saliva samples at 0 weeks, 32 weeks and 6 months postnatal | — |
Countries
United Kingdom
Outcome results
None listed