Effect of caffeine and citrulline malate on resistance exercise and jumping performance: a randomized double-blind placebo-controlled crossover study

Effect of isolated and combined ingestion of caffeine and citrulline malate on resistance exercise and jumping performance: a randomized double-blind placebo-controlled crossover study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN11694009

Enrollment

Registered

2023-02-10

Start date

2021-09-01

Completion date

Unknown

Last updated

2023-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sports-related outcomes Nutritional, Metabolic, Endocrine

Interventions

Study design A randomized, double-blind, placebo-controlled, crossover trial is being used to investigate the isolated and combined effects of caffeine and CitMal on countermovement ju

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged between 18 and 45 years old 2. A minimum of 12 months of resistance training experience 3. Currently performing resistance training at least two times per week 4. Able to perform the barbell back squat and bench press with 120% and 100% of body mass for males and 100% and 70% of body mass for females

Exclusion criteria

Exclusion criteria: 1. Smoking 2. Pregnancy or lactating

Design outcomes

Primary

Measure	Time frame
1. Jump height (cm) measured using a force plate at every trial before the strength test and after warmup 2. Maximal power (W) measured using a force plate at every trial before the strength test and after warmup 3. Rate of force development (kN/s) measured using a force plate at every trial before the strength test and after warmup 4. Peak force (N/kg) measured using a force plate at every trial before the strength test and after warmup 5. Maximal strength measured using a barbell and plates for loading at every trial after the jump test 6. Number of repetitions to failure with barbell and plates for loading on every trial after the jump test	—

Measure

Time frame

1. Jump height (cm) measured using a force plate at every trial before the strength test and after warmup 2. Maximal power (W) measured using a force plate at every trial before the strength test and after warmup 3. Rate of force development (kN/s) measured using a force plate at every trial before the strength test and after warmup 4. Peak force (N/kg) measured using a force plate at every trial before the strength test and after warmup 5. Maximal strength measured using a barbell and plates for loading at every trial after the jump test 6. Number of repetitions to failure with barbell and plates for loading on every trial after the jump test

—

Secondary

Measure	Time frame
Pain perception measured using a numerical rating scale straight after the number of repetitions to failure test for both bench press and back squat	—

Countries

Norway

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 10, 2026