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Study of a device for detecting diabetic eye disease

Implementation and evaluation of a mobile retinal image acquisition system for screening diabetic retinopathy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN11684778
Enrollment
578
Registered
2021-12-30
Start date
2022-06-15
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic retinopathy Eye Diseases Diabetic retinopathy

Interventions

In this study, individuals with diabetes will be assessed for diabetic retinopathy with the smartphone-based handheld fundus camera EyeFundusScope (Fraunhofer AICOS, Portugal) operated by non-ophthalm

Sponsors

Fraunhofer Portugal Research
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Diabetes mellitus diagnosis 2. 18-90 years old

Exclusion criteria

Exclusion criteria: 1. Blindness 2. Strabismus 3. Retinal detachment 4. Blepharospasm 5. No autonomy to remain seated 6. Sensitivity to light due to medication, recent photodynamic therapy, or other reason 7. Pregnant or breastfeeding women

Design outcomes

Primary

MeasureTime frame
Diagnostic accuracy of EyeFundusScope for diabetic retinopathy screening, measured using sensitivity, specificity, predictive values and likelihood ratios at the time of retinal image acquisition

Secondary

MeasureTime frame
1. Image quality measured in four levels and classified by ophthalmologists at the time of retinal image acquisition 2. Technological functioning measured using the number of eyes in which it was not possible to acquire images, and the number of technical failures of both the EyeFundusScope and the information system, at the time of retinal image acquisition 3. Usability of the EyeFundusScope measured using the proportion of healthcare professionals who report ease of use, the score of the System Usability Scale, qualitative analyses of the observation and the mean time required to perform retinal image acquisition with the EyeFundusScope, at the time of retinal image acquisition 4. Acceptance of the EyeFundusScope measured using questionnaires and qualitative analysis of interviews and observations at the time of retinal image acquisition 5. The association of patients’ clinical characteristics with the accuracy and the quality of the images of the EyeFundusScope, measured using odds ratios at the time of retinal image acquisition 6. Inter and intra-operator agreement and reliability of the EyeFundusScope measured using kappa statistics and overall observed agreement at the time of retinal image acquisition 7. Ground truth optimization for the training of the algorithms before the calculation of measures listed above

Countries

Portugal

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026