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The invasive dentistry - endocarditis association study

The Invasive Dentistry - Endocarditis Association case-crossover study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN11684416
Enrollment
1483
Registered
2016-07-12
Start date
2016-09-01
Completion date
Unknown
Last updated
2022-06-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infective endocarditis Infections and Infestations

Interventions

This is an observational study using UK national databases to see if infective endocarditis hospital admissions occur with higher frequency in the 3 months immediately following a course of treatment

Sponsors

University of Sheffield
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. All IE hospital admissions in England between 1st April 2010 and 31st March 2016 recorded on the Hospital Episode Statistics database 2. All individuals within England who attended an NHS dentist for a check up or treatment between 1st April 2009 and 31st March 2016 and whose data is recorded on the NHS Business Services Dental Database

Exclusion criteria

Exclusion criteria: 1. Individuals falling into the target population without a known NHS number 2. Individuals with missing or corrupt records

Design outcomes

Primary

MeasureTime frame
The incidence of infective endocarditis (IE) hospital admissions in the 3 months immediately following courses of dental treatment that includes an invasive dental procedure, coopered to the incidence of IE hospital admissions during later 3 month periods (3-6, 6-9 and 9-12 months after)

Secondary

MeasureTime frame
1. The frequency of courses of dental treatment involving an invasive dental procedure (cases) before an IE diagnosis 2. The frequency of course of dental treatment that did NOT involve an invasive dental procedure The two outcomes are then compared.

Countries

England, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 12, 2026