Parkinson's Disease Nervous System Diseases Parkinson's Disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Current exclusion criteria as of 05/01/2021: 1. Confirmed diagnosis of Parkinson's disease (PD) 2. Stage I-III Hoehn and Yahr Scale (appendix) 3. Mild to severe gait disturbance with a score of =2 on the Unified Parkinson’s disease Rating Scale (UPDRS) item 29 4. Able to walk independently with or without a walking aid greater than 100m 5. Stable medication for more than 3 weeks 6. Able to speak and understand English without assistance 7. Have a tablet/laptop with a webcam, that is Microsoft Teams compatible 8. Access to a stable internet connection _____ Previous inclusion criteria: 1. Confirmed diagnosis of Parkinson's disease (PD) 2. Stage I-III Hoehn and Yahr Scale (appendix) 3. Mild to severe gait disturbance with a score of =2 on the Unified Parkinson’s disease Rating Scale (UPDRS) item 29 4. Able to walk independently with or without a walking aid greater than 100m 5. Stable medication for more than 3 weeks 6. Able to speak and understand English without assistance 7. Available to attend an exercise class in Aberdeen for 12 weeks
Exclusion criteria
Exclusion criteria: 1. Secondary or atypical Parkinsonism 2. Severe, unpredictable episodes of motor fluctuation 3. Use of medications known to interfere with cognitive function 4. History of neurological diseases other than PD 5. Any unstable mental or physical condition that prevent consenting and participating in the exercise intervention 6. Unstable or uncontrolled medical conditions
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Feasibility and acceptability assessed via semi-structured interviews at 30 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| The course of Parkinson's disease measured using the following at 0, 6, 18, and 30 weeks: 1. Unified Parkinson’s Disease Rating Scale (UPDRS) 2. Lille Apathy Rating Scale (LARS) 3. Parkinson Fatigue Scale (PFS) 4. Timed Up and Go (TUAG) 5. 10 meter walk test (10MWT) 6. Parkinson’s Anxiety Scale (PAS) 7. Geriatric Depression Scale (GDS) 8. 6 minute walk test (6MWT) 9. Activities-Specific Balance Confidence (ABC) Scale 10. Physical Activity Scale for the Elderly (PASE) 11. Schwab and England Activities of Daily Living Scale 12. MiniBESTest 13. Physical Activity Scale for individuals with Physical Disability (PASIPD) 14. Parkinson’s Disease Questionnaire 39 (PDQ-39) 15. Self-Efficacy for Exercise Scale 16. Functional Gait Assessment- FGA 17. Nottingham Health Profile 18. Warwick Edinburgh Mental Health and Wellbeing Scale | — |
Countries
Scotland, United Kingdom