MIA-MS: The effectiveness of an online mindfulness based cognitive therapy intervention programme in improving well-being in people with multiple sclerosis

The effectiveness of an online mindfulness based cognitive therapy intervention programme in improving well-being in people with multiple sclerosis: a randomised controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN11615285

Enrollment

Registered

2013-04-24

Start date

2013-02-10

Completion date

Unknown

Last updated

2017-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple sclerosis Nervous System Diseases Multiple sclerosis

Interventions

After completing the baseline/screening questionnaire participants will be randomly allocated to the intervention or a 4 month waitlist control group. Intervention group: 12 sessions

3 a week over a course of 4 weeks. The intervention will be delivered online and will have links to the 12 sessions as well as details to contact us, outside support they can seek, the original partic

Eligibility

Inclusion criteria

Inclusion criteria: 1. People self reported probable or definite diagnosis of multiple sclerosis based on medical opinion. 2. Participants will be over 18 and not currently experiencing symptoms of psychosis.

Exclusion criteria

Exclusion criteria: 1. People without a probable or definite diagnosis of multiple sclerosis 2. People under 18

Design outcomes

Primary

Measure	Time frame
Depression, Anxiety and Stress and coping measured on self report questionnaires, Depression, Anxiety and Stress Scales (DASS), Coping with Multiple Sclerosis Scales (CMSS) Both primary and secondary outcomes will be measured at baseline, before commencing the intervention programme or wait list wait. The same measurements will be obtained at 4 weeks (after completing the intervention programme/wait list) and again at a 4 week follow-up for both groups. Participants will be invited to answer a questionnaire at longer follow at 3 months. Participants in the waitlist control group will be invited to take part in the intervention at this point. In addition to the above listed assessment time point, those who complete the intervention and follow-up will be followed up at 1 year.	—

Measure

Time frame

Depression, Anxiety and Stress and coping measured on self report questionnaires, Depression, Anxiety and Stress Scales (DASS), Coping with Multiple Sclerosis Scales (CMSS) Both primary and secondary outcomes will be measured at baseline, before commencing the intervention programme or wait list wait. The same measurements will be obtained at 4 weeks (after completing the intervention programme/wait list) and again at a 4 week follow-up for both groups. Participants will be invited to answer a questionnaire at longer follow at 3 months. Participants in the waitlist control group will be invited to take part in the intervention at this point. In addition to the above listed assessment time point, those who complete the intervention and follow-up will be followed up at 1 year.

—

Secondary

Measure	Time frame
Mindfulness, illness perceptions measured on self report questionnaires (Cognitive and Affective Mindfulness Scale? Revised (CAMS-R); Illness Perceptions Questionnaire - Revised (IPQ-R)	—

Countries

Australia, Canada, Ireland, United Kingdom, United States of America

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026