Investigating the root cause of strabismus in children

The role of oculoproprioception in the neural control of ocular alignment: Understanding disease mechanisms in strabismus

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN11588626

Enrollment

102

Registered

2026-02-02

Start date

2025-08-13

Completion date

Unknown

Last updated

2026-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Strabismus (squint or crossed eyes), specifically Partially Accommodative Esotropia (PAE) and Fully Accommodative Esotropia (FAE). Eye Diseases

Interventions

This is an observational study, there is no intervention. Below is a description of the measurements. The study assesses oculoproprioceptive function in children with primary accommodative esotropia

Eligibility

Sex/Gender

All

Age

4 Years to 5 Years

Inclusion criteria

Inclusion criteria: For the children with strabismus: 1. Diagnosis – FAE or PAE For All Children: 1. Hyperopia corrected to normal using glasses 2. Age 4- to 5-years-old 3. No previous surgery on the eye muscles

Exclusion criteria

Exclusion criteria: 1. No underlying neurological disease such as a brain lesion or extraocular muscle paresis 2. The parents do not have the capacity to give informed consent, and the child has the capacity to assent. 3. Inability to speak English 4. Previous surgery on the extraocular muscles

Countries

Scotland, United Kingdom

Contacts

Public ContactDaniela Balslev

db87@st-andrews.ac.uk+44 (0)1334 462097

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 3, 2026