Surgical treatment of localized prostate cancer Surgery
Conditions
Interventions
All patients who are candidates for radical prostatectomy will be randomised into two groups:
- Group A: will undergo laparoscopic radical prostatectomy (LRP)
- Group B: will undergo robot-assisted radical prostatectomy (RALP).
A two-armed randomisation scheme will be generated by means of a specific "query" to the website www.randomization.com. A typical v
Sponsors
University of Turin
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. Aged between 50 and 75 years 2. Diagnosed with localised or locally advanced prostate adenocarcinoma (clinical stage T1-2 or T3, in each case N0, M0) 3. Gleason score between 2 and 10 4. PSA <20ng/ml
Exclusion criteria
Exclusion criteria: Patients who withdraw consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Postoperative urinary continence will be assessed with ICS questionnaire at 1, 3, 6, 12, 60 and 120 months after surgery. 2. Postoperative erectile function will be assessed with IIEF5 questionnaire at 1, 3, 6, 12, 60 and 120 months after surgery. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Serum PSA levels will be assessed at 1, 3, 6, 12, 60 and 120 months after surgery 2. Intraoperative complications will be assessed using Clavien-Dindo scale during the intervention 3. Postoperative complications will be assessed using Clavien-Dindo scale at 1, 12, 60 and 120 months after surgery | — |
Countries
Italy
Outcome results
None listed