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The effect of moringa oleifera leaf extract on the inflammation status of breast cancer patients receiving hormonal therapy

The effect of moringa oleifera leaf extract on the inflammation status of breast cancer patients receiving aromatase inhibitor therapy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN11510869
Enrollment
70
Registered
2022-12-01
Start date
2022-06-01
Completion date
Unknown
Last updated
2023-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Moringa Oleifera leaf extract reduces inflammation status of breast cancer patients with estrogen receptor (+) and estrogen receptor (+) receiving Aromatase Inhibitor Therapy Cancer

Interventions

The research sample was divided into 2 groups: control and treatment groups. The treatment group received a 300 mg capsule of Moringa leaf extract with a daily dose of 600 mg and dicl

Sponsors

Diponegoro University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Breast cancer patient 2. Post menopause 3. Imunohistokimia Estrogen receptor (+), Progesteron receptor (+) 4. Received aromatase inhibitor 5. Patient with Aromatase Inhibitor-Associated Musculoskeletal Syndrome

Exclusion criteria

Exclusion criteria: 1. Emergency condition that needs operation 2. Visceral metastasis 3. History of previous degenerative joint and soft tissue disease (osteoarthritis/rheumatoid arthritis). 4. History of fracture during the last 6 months

Design outcomes

Primary

MeasureTime frame
Inflammation status is measured using data on the levels of ESR, CRP, CPK, and ANA. Data is gathered pre-treatment and after treatment (30 days)

Secondary

MeasureTime frame
Measured using blood test: 1. Erythrocyte Sedimentation rate (ESR) measured at pre-treatment and after treatment (30 days) 2. C-Reactive Protein (CRP) measured at pre-treatment and after treatment (30 days) 3. Anti-Nuclear Antibody (ANA) measured at pre-treatment and after treatment (30 days) 4. Creatine Phosphokinase (CPK) measured at pre-treatment and after treatment (30 days)

Countries

Indonesia

Contacts

Public ContactYan wisnu Prajoko
yanwisnuprajoko@lecturer.undip.ac.id+62 812-2904-279

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026