In-vitro fertilization Pregnancy and Childbirth
Conditions
Interventions
All patients decided for Frozen Embryo Transfer (FET) will be identified, informed consent taken at the start of FET cycle, and the randomization will be performed only when endometrial thickness reac
Sponsors
University Malaya Medical Centre
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Women undergoing for frozen embryo transfer 2. Medicated frozen embryo transfer cycle 3. Endometrial thickness > 8mm on starting the luteal phase support with trilaminar appearance on sonography 4. Embryo transfer (embryo frozen at day 5)
Exclusion criteria
Exclusion criteria: 1. Fresh embryo transfer 2. Transfer of 3 or more embryos
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Viable pregnancy with evidence of intra-uterine gestation sac/sacs and presence of fetal heart/hearts activity at 10 weeks after embryo transfer | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Implantation rate - the number of gestational sacs observed by ultrasound divided by the number of embryos transferred (usually expressed as a percentage) at 10 weeks after embryo transfer 2. Miscarriage rate - non viable pregnancy diagnosed by ultrasound at 10 weeks after embryo transfer 3. Ectopic pregnancy diagnosed by ultrasound or laparoscopically at 10 weeks after embryo transfer 4. Multiple pregnancies diagnosed by ultrasound scan at 10 weeks after embryo transfer 5. Biochemical pregnancy - serum HCG (>50IU/ml) at 2 weeks after embryo transfer | — |
Countries
Malaysia
Contacts
Public ContactAtikah Mohamed Halim
Outcome results
None listed