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Promoting rapid diagnosis of tuberculosis

TB Reach 4 - Randomised controlled trial of rapid diagnosis of tuberculosis on the mobile X-ray unit (MXU) using Cepheid PCR system

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN11432500
Enrollment
80
Registered
2016-08-04
Start date
2013-09-01
Completion date
Unknown
Last updated
2017-10-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Specialty: Respiratory disorders, Primary sub-specialty: Respiratory disorders Respiratory Tuberculosis

Interventions

Those who have consented to participating in the study will be randomised using a text messaging randomisation service provided by Sealed Envelope (http://www.sealedenvelope.com). A stratified randomi

Sponsors

University College London
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Any hard to reach patient, 16 years of age or older with an abnormal chest X-ray suggestive of active pulmonary TB identified through MXU screening.

Exclusion criteria

Exclusion criteria: Persons who refuse to participate.

Design outcomes

Primary

MeasureTime frame
Number of clinic visits needed for exclusion or confirmation of tuberculosis diagnosis is determined by checking TB clinic notes at 3 months post referral.

Secondary

MeasureTime frame
1. Time to diagnostic conclusion through smear microscopy and culture investigations is determined by checking TB clinic notes at 3 months post referral. 2. Time to onset of appropriate treatment is determined by checking TB clinic notes at 3 months post referral 3. Time to isolation for infectious cases is determined by checking hospital in-patient records at 3 months 4. Number of participants who develop active TB from the initial X-ray on the MXU is determined by checking surveillance record at 12 months post referral

Countries

United Kingdom

Contacts

Public ContactAndrew Hayward
a.hayward@ucl.ac.uk+44 (0)20 7794 0500

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026