Differences in pain relief after open or laparoscopic colorectal cancer surgery with epidural or intravenous medication

Thoracic epidural analgesia versus patient-controlled intravenous analgesia for patients undergoing open or laparoscopic colorectal cancer surgery, an observational study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN11426678

Enrollment

422

Registered

2021-02-26

Start date

2017-10-27

Completion date

Unknown

Last updated

2025-03-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Analgesia approaches for laparoscopic surgery Surgery

Interventions

The study was performed in patients scheduled for laparoscopic or open colonic resections with either thoracic epidural (TEA) or intravenous opioid pain (PCIA) relief management. Data collection was p

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All adult patients who underwent colorectal cancer surgery between 2014 and 2016, with ASA status I-IV were included

Exclusion criteria

Exclusion criteria: 1. No postoperative thoracic epidural analgesia of patient controlled analgesia 2. Double cases 3. Missing data

Design outcomes

Primary

Measure	Time frame
Postoperative pain measured using the NRS postoperatively and at day 1, 2 and 3, both at rest and during movement	—

Secondary

Measure	Time frame
1. Length of stay (days) measured using patient records 2. Incidence of epidural related side effects measured by clinical observation postoperatively at day 1, 2 and 3 3. Major complications measured using patient records for 30 days after surgery 4. 5-year survival measured using patient records	—

Countries

Netherlands

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 10, 2026