We are looking at both worry and persecutory delusions in individuals with psychotic diagnoses (schizophrenia, schizoaffective disorder, and delusional disorder). Mental and Behavioural Disorders
Conditions
Interventions
We are utilising a waiting list control design. This means that in the initial phase of the trial, one group of participants will be randomly allocated to attend the first 8 week worry group (group A)
Sponsors
Oxleas NHS foundation Trust
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. A current persecutory delusion 2. The delusion has persisted for at least 6 months 3. A current clinical diagnosis of schizophrenia, schizoaffective disorder or delusional disorder 4. A clinically significant level of worry, as indicated by scores of 45 or more on the Penn state worry questionnaire 5 Aged between 18-65
Exclusion criteria
Exclusion criteria: 1. A primary diagnosis of alcohol or substance dependency 2. Organic syndrome or learning disability 3. A command of spoken English inadequate for engaging in psychological therapy 4. Judged as unable to give informed consent 5. In an acute phase of symptomatic distress such that they require inpatient admission 6. Currently in receipt of another form of Cognitive Behaviour Therapy (CBT)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Worry: To measure worry we will be using the Penn-State Worry questionnaire. This is a 16 item self-report questionnaire, each item rated on a five point Likert scale (rated 1 to 5). The total score on this measure will be used to identify levels of worry (NB: To be included in the study, the total at baseline must be over 45) 2. Delusional Distress: This will be measured using the Psychotic Symptom Rating Scale (PSYRATS) – delusions part, Factor 2 subscale and the The Green Paranoid Thoughts Scale (GPTS) - Part B distress subscale. The PSYRATS is a semi-structured interview comprising of 6 items, each rated on a 5 point ordinal scale (0-4). The GPTS is a 32-item self-report measure (each item rated on a 5-point Likert scale) 3. Overall Paranoia & Persecutory Ideation will be measured by the PSYRATS - delusions part (Total Score) and GPTS - Part B Total score (see above description of measures) The key time points for measurement in this trial are as follows: 1. Recruitment 2. T0 (the time when the first worry group commences) 3. T1 (the time at which the first worry group finishes i.e. 8 weeks after T0) 4. T2 (the time at which the second worry group commences, i.e. 4 weeks after T1) 5.T3 (the time at which the second worry group finishes, i.e. 8 weeks after T2) and 6. T4 (a one-month follow up session 4 weeks after the second group finishes) All participants will complete the PSYRATS, PSWQ and GPTS at recruitment. For those participants randomised to receive the first worry group (i.e. group A), they will also complete the PSYRATS, GPTS, and PSWQ at T0, T1, and T2. For those participants randomised to receive the second worry group (i.e. the waiting list control, group B), they will also complete the PSYRATS, GPTS, and PSWQ and T0, T1, T2, T3 and T4. | — |
Secondary
| Measure | Time frame |
|---|---|
| In order to control for the potential effects of demographic and IQ variables we will be collecting the following data at the recruitment stage of the trial. 1.IQ: to provide an estimate of premorbid IQ we will administer the Wechsler Test of Adult Reading (WTAR) – This measure provides an estimate of premorbid IQ 2.Demographic data: .demographic data detailing participants' age, gender, marital status, employment status. care status (i.e. open to which mental health team), diagnosis, and current medication will be obtained from the medical records at the recruitment stage of the trial. | — |
Countries
United Kingdom
Contacts
Public ContactLouise Isham
Outcome results
None listed