Assessment of lung water in patients with low blood pressure after infection

Comparison of three methods of lung ultrasound with the transpulmonary thermodilution technique for assessment of extravascular lung water in patients with septic shock

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN11419081

Enrollment

Registered

2015-02-04

Start date

2013-09-01

Completion date

Unknown

Last updated

2018-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Septic shock Circulatory System Septic shock

Interventions

1. Total B-line scores 2. BLUE points 3. Scanning eight regions These three methods of lung ultrasound were used on each patient to assess extravascular lung water and the results were compared with t

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Age 18 years old or over 2. Septic shock requiring central venous catheterisation and arterial catheterisation for continuous pressure monitoring

Exclusion criteria

Exclusion criteria: 1. Valvular heart disease 2. Pregnancy 3. Acute or history of pulmonary embolism 4. Lung resection surgery 5. Acute respiratory distress syndrome 6. Interstitial lung diseases 7. Mulitilobar pneumonia 8. Pleural diseases

Design outcomes

Primary

Measure	Time frame
Best method of lung ultrasound to diagnose pulmonary oedema in patients with septic shock: cutoff point of extravascular water index measured by transpulmonary thermodilution greater than 10 mL/kg predicted bodyweight, which is correlated with a pulmonary capillary wedge pressure of greater than 20 mmHg to indicate pulmonary oedema	—

Secondary

Measure	Time frame
Cutoff point of total B-line scores to predict extravascular lung water index of 10 mL/kg or more	—

Countries

Thailand

Contacts

Public ContactPattarin Pirompanich

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 25, 2026