Vestibular dysfunction Ear, Nose and Throat
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Confirmed unilateral vestibular schwannoma 2. Confirmed unilateral Meniere’s disease 3. Suspected peripheral vestibular dysfunction (patients attending ENT clinic pre-diagnosis) 4. Understand verbal and written English 5. At least 18 years old
Exclusion criteria
Exclusion criteria: 1. Other afflictions which may affect the control of balance and vestibular function e.g. neurological conditions such as stroke, Parkinson's disease, cerebellar ataxia, dementia. 2. Electronic implants (including cochlear implants, pacemakers and bone-anchored hearing aids) 3. Uncontrolled heart disease or uncontrolled mental illness 4. Any patient with eardrum perforation or other damage/infection of the outer ear will be excluded from caloric irrigation 5. Any patient with severe tinnitus will be excluded from air-conducted VEMPs 6. Any patients with neck pain will be excluded from vHIT
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Asymmetry in vestibular function determined using EVS and the other vestibular tests at a single timepoint | — |
Secondary
| Measure | Time frame |
|---|---|
| The diagnostic utility of EVS in a group of patients with suspected vestibular deficit prior to definitive diagnosis, determined by comparing EVS symmetrical vestibular measurements against caloric irrigation, vHIT and VEMPS values obtained at a single visit. These patients will then be followed to determine their diagnosis for a minimum of 3 years. | — |
Countries
England, United Kingdom